Cannabidiol, or CBD, is a chemical compound in marijuana with a variety of uses . Here are 7 benefits of CBD oil. As more and more states legalize the use of marijuana, a product known as CBD oil has surged in popularity. A chemical compound found in the cannabis plant. OTHER NAME(S). 2-[(1R,6R)Methylpropenylcyclohexenyl] pentylbenzene-1 ,3-diol, CBD. . Show More · Read Reviews (47).
Side Effects & Oil: CBD Uses, Hemp Benefits,
A study aimed to compare the effects of a simulation public speaking test on healthy control patients and treatment-naive patients with social anxiety disorder. A total of 24 never-treated patients with social anxiety disorder were given either CBD or placebo 1. Researchers found that pretreatment with CBD significantly reduced anxiety , cognitive impairment and discomfort in their speech performance, and significantly decreased alertness in anticipation of their speech.
The placebo group presented higher anxiety, cognitive impairment and discomfort. A study published in the Journal of Pharmacology and Experimental Therapeutics found for the first time that CBD potently and selectively inhibited the growth of different breast tumor cell lines and exhibited significantly less potency in non-cancer cells.
In , researchers added light on the cellular mechanism through which CBD induces cell death in breast cancer cells. They showed that CBD induced a concentration-dependent cell death of both estrogen receptor-positive and estrogen receptor-negative breast cancer cells. They also found that the effective concentrations of CBD in tumor cells have little effect on non-tumorigenic, mammary cells. CBD behaves as a non-toxic compound and studies show that doses of milligrams per day for six weeks did not show any overt toxicity in humans, suggesting that it can be used for prolonged treatment.
Cannabis has been used for centuries for the suppression of nausea and vomiting. Research has revealed that among more than 80 cannabinoid compounds found in marijuana, both the intoxicant THC and the non-intoxicant CBD helps to get rid of nausea and vomiting in animal studies. Researchers found that CBD acts in a diphasic manner , meaning that in low doses it suppresses toxin-induced vomiting, but in high doses it increases nausea or has no effect. Nineteen responses met the inclusion criteria for the study: The average number of anti-epileptic drugs tried before using CBD cannabis was Of these, two 11 percent reported complete seizure freedom, eight 42 percent reported a greater than 80 percent reduction in seizure frequency, and six 32 percent reported a 25—60 percent seizure reduction.
Other beneficial effects included increased alertness, better mood and improved sleep; while side effects included drowsiness and fatigue. After three months of treatment, 39 percent of the 23 patients had more than a 50 percent reduction in seizures, with a 32 percent median reduction. These preliminary results support the animal studies and survey reports that CBD may be a promising treatment for treatment-resistant epilepsy, and it is generally well-tolerated in doses up to 25 milligrams per kilogram of body weight.
A study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in CBD-treated mice. A histological examination of the pancreatic islets of the CBD-treated mice revealed significantly reduced insulitis. In , the American Journal of Medicine published a study that highlighted the impact of marijuana use on glucose, insulin and insulin resistance among U.
The study included 4, adult men and women from the National Health and Nutritional Examination Survey from to Of the participants, were current marijuana users and 1, were past users. The researchers found that current marijuana use was associated with 16 percent lower fasting insulin levels. They also found significant associations between marijuana use and smaller waist circumferences, a factor connected to the onset of diabetes symptoms.
A study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, CBD proved to reduce the vascular hyperpermeability which causes leaky gut associated with such environments. As the popularity of CBD products continues to grow, more manufacturers are jumping on the bandwagon. This can be a great thing for consumers who are looking to get the best CBD products out there.
But it also requires careful research before making a purchase. Although the research on the medicinal use of cannabis is strong, several studies indicate that the recreational use of cannabis can have persistent adverse effects on mental health. Most recreational users will never be faced with such persistent mental illness, but in some individuals cannabis use leads to undesirable effects, including cognitive impairment, anxiety, paranoia and increased risks of developing chronic psychosis or drug addiction.
Some studies show that CBD can counteract these adverse effects, but more research is needed, as most of this research is done on animals or is based on anecdotal reports.
There are several ways to use CBD, including in capsule, topical, edible or drop forms. I recommend ingesting CBD oil using a dropper because this is the easiest way to stay in control of exactly how much you are taking. Plus, pure CBD oil will not contain additives that come with side effects. Remember, when you are using CBD oil or any kind of cannabis product, you must read the product label to determine the best dose for you.
Where do you buy CBD oil? You may have noticed that CBD products are everywhere these days. To separate the highest quality products from the rest, look for one that has a certificate of analysis, or COA. This means that the manufacture tests the product for contaminants, and it meets lab standards. I recommend avoiding vape pens because many contain a solvent called propylene glycol. When you burn this solvent at high temperatures, it can degrade into formaldehyde and cause danger adverse reactions.
CBD is one of over 60 compounds found in cannabis that belong to a class of ingredients called cannabinoids; it is the major nonpsychoactive component of Cannabis sativa. Research shows that CBD benefits include its ability to act as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic agent. It is a potential medicine for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety and schizophrenia. CBD derived from industrial hemp is legal across the U.
However, e ach state has specific requirements and conditions that need to be followed in order to use marijuana-derived CBD legally. Josh Axe is on a mission to provide you and your family with the highest quality nutrition tips and healthy recipes in the world The most common types of CBD available include: Tinctures are the most popular way to use CBD oil, likely because you can easily gauge exactly how much CBD you are ingesting. At a time when we are trying to reduce the use of pain relievers, CBD oil can be an effective approach to managing the pain of arthritis.
However, its effectiveness will vary from person to person. Work with your doctor to sort out the right balance of CBD oil, other medications, and self-care. This may work better than the medications you have been taking. We picked linked items based on the quality of products, and list the pros and cons of each to help you determine which will work best for you.
We partner with some of the companies that sell these products, which means Healthline UK and our partners may receive a portion of revenues if you make a purchase using a link s above.
Article last updated by Yvette Brazier on Thu 2 August Visit our Osteoarthritis category page for the latest news on this subject, or sign up to our newsletter to receive the latest updates on Osteoarthritis.
All references are available in the References tab. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medication Sativex in the treatment of pain caused by rheumatoid arthritis [Abstract]. Rheumatology , 45 1 , 50— FDA approves first drug comprised of an active ingredient derived from marijuana to treat rare, severe forms of epilepsy [Press release].
European Journal of Pain , 20 6 , — Involvement of the endocannabinoid system in osteoarthritis pain [Abstract]. European Journal of Neuroscience , 39 3 , — Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis [Abstract]. Pain , 10 , Cannabinoids in the management of difficult to treat pain. Therapeutics and Clinical Risk Management , 4 1 , — The abnormal cannabidiol analogue O reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55 [Abstract].
Neuroscience Letters , 1 , 72— MNT is the registered trade mark of Healthline Media. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional.
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Register take the tour. Table of contents What is CBD oil? CBD oil is the oil derived from hemp, which is a type of cannabis plant. As of this writing, there are 30 states that have legalized the sale of cannabis in some form, whether that be medicinally or recreationally.
Because federal law continues to outlaw the production and sales of cannabis aside from the CBD oil and hemp seed oil from hemp plants, it is illegal for states that have legalized cannabis to sell products across state borders. As detailed previously, hemp oil in the United States refers to the oil extracted from the stalk of the hemp plant. The extraction process involves using a solvent to extract the oil from the hemp stalk.
There are numerous solvents used commercially, all of which have benefits and drawbacks. In this extraction method, the hemp is exposed to high-pressure, low-temperature CO2 gas, which helps isolate and preserve the cannabinoids in the oil. The drawbacks include slow extraction time and high production costs, meaning that these products will be on the more expensive end.
Ethanol extraction is safe and nontoxic in small amounts. The main drawback is that ethanol-extraction destroys the plant waxes, which some claim have health benefits.
Olive oil is safe and cost-effective, and comes with a slew of health benefits from reducing inflammation to boosting immunity.
These solvents do a great job of extracting the cannabinoids from hemp, but some remain after the extraction process and are potentially harmful to your lungs. Because it takes a significantly larger amount of hemp stalks to produce hemp oil, there is an increased risk of contamination of toxins contained within the plant.
This is a result of hemp's strong bio-accumulator properties, where it pulls toxins from the soil it grows in. Many hemp oils are also known to lack the full spectrum of terpenes and other cannabinoids that are believed to act synergistically with the CBD, meaning that consumers receive less of a benefit. That being said, there are some brands that test rigorously to make sure that the CBD content, as well as the terpenes and other cannabinoids, are up to par.
It's a good sign if they offer to provide a certificate of analysis, which will tell you what kind of compounds are in the hemp oil and in what concentrations.
Hemp oil can be found in many different delivery forms. Hemp oil can be consumed orally, applied topically or sublingually, or smoked via vaporization. Vaporization and sublingual application of hemp oil allows for a fast onset-of-action of the CBD, whereas pills and edible products can take 30 to 90 minutes on average to take effect. Topical hemp oil can be applied directly to areas of pain or inflammation, though it can also be absorbed into the systemic circulation.
When talking about the benefits of hemp oil, what we are mostly really referring to are the benefits of the CBD within the hemp oil. While there is still a need for higher-quality studies regarding the benefits of CBD oil, the available research and clinical evidence are compelling:. The CBD in hemp oil has been used by patients with recalcitrant epilepsy for decades. A recent retrospective study out of Israel showed significant decreases in seizure activity with the use of CBD-enriched medical cannabis.
In this study, 52 percent of patients had a greater than 50 percent reduction in seizure activity. CBD oil has been shown to decrease activity in the limbic part of the human brain, which is responsible for our "fight-or-flight" response. A study in found that CBD oil significantly reduced anxiety and cognitive impairment compared to placebo.
There are some animal studies that show improved markers for pain and inflammation with the use of topical hemp oil. However, most of the current data studying the benefits of cannabinoids for pain show the combination of CBD with THC to be the most effective for pain.
A small study on mice in showed that CBD oil prevented the development of social recognition deficit, which is a common occurrence in Alzheimer's disease. But more research is needed to validate these findings in humans! CBD is also a potent antioxidant, which means it protects your body from free radical damage, and is thought to exhibit anti-depressant, anti-nausea, gut-protective, and immune-system-balancing effects. But again, more research needs to be done in all these areas.
Each person has a different genetic and biochemical makeup. This means people will respond to different doses of CBD, so you will have to test to see which doses are best for you.
Start at a lower dose of hemp oil and increase slowly to achieve the desired effect. Remember that if you choose an oral product, it can take 30 to 90 minutes to notice any benefit. Spacing out your doses—rather than one large dose once a day—can help you maintain adequate blood levels. Sometimes smaller doses can have a more substantial effect than larger doses.
Remember that you are genetically and biochemically distinct from everyone else and need to discover the best dosage for you.
? CBD hemp oil, in small clear jar with a bag of hemp seeds, marijuana. CBD oil is the oil derived from hemp, which is a type of. 5 Health Benefits of CBD Oils by Canabo Medical Inc. Cannabidiol's impact ' high' associated with cannabis use), making it a safe and effective option effective pain relief without inducing adverse side effects in patients. Is CBD the same as cannabis? While the majority of research done into the effects of CBD oil has been based on animal any negative effects, as with any treatment – natural or otherwise – there are possible side effects.