The public profile of CBD has soared in recent years, with users using it to treat all manner of ailments and conditions. It can be consumed in a variety of ways. As patients start to understand how CBD can be used to alleviate their symptoms, they are often faced with a choice between using products. CBD isolate is a pure, crystalline powder that contains 99% pure CBD. . I will be able to help you more if I have a better understanding of the.
Isolate: Understanding CBD
Further, studies heavily suggest that CBD may also be beneficial in the treatment of marijuana and tobacco addiction. One reason that CBD may be effective as treatment for addictive disorders is its ability to ease the anxiety that leads people to crave drugs like heroin. At sufficient doses mg , CBD can alleviate situational anxiety, such as public speaking. Interestingly, cannabis cultivars, or strains, that are high in CBD and low in THC are better than other cultivars for alleviating depression.
But when used over a long period of time, any kind of cannabis could make depression worse. There is a massive amount of scientific research being done on CBD right now, and we are likely to see many medical breakthroughs in the next decade. It found that extract taken from whole plant CBD-rich cannabis is therapeutically superior to single-molecule extract.
The scientists behind this study noticed that science had been utilizing pure, single-molecule CBD, which resulted in a bell-shaped dose-response curve. The study from Israel essentially documented the synergistic effects of whole plant cannabinoid profiles; as noted above, this is the entourage effect. The difference here, however, is that this most recent study dove into what extent whole-plant CBD can be more therapeutic than single-molecule CBD extract.
Although both hemp and marijuana are cannabis, hemp produces less than 0. This means that producing a single 10 mL dose of CBD would require the cultivation and extraction of far more hemp than it would from whole-plant marijuana; thus raising the risk of exposing users to more contaminants.
Also, CBD derived from industrial hemp lacks the the incredibly diverse profile of different cannabinoids and terpenes found in whole-plant marijuana. CBD derived from hemp boasts a greatly weaker entourage effect. Federal law in the United States prohibits the use of hemp leaves and flowers to make drug products. In this case, the differences between industrial hemp and whole-plant marijuana are far less significant.
Consumers should be aware that a handful of hemp products on the market pay lip service to governmental regulations by labeling themselves as hemp, despite containing cannabinoids and terpenoids. A potent pain-reliever, Cannatonic hails from Spain and stands as one of the earliest cultivars to be bred for its high CBD content.
This cultivar is a cross between MK Ultra and G13 Haze, and it helps relieves anxiety, muscle spasms, pain, and migraines while providing uplifting energy. Cannatonic tends to relax and loosen muscles without locking users to their couches. This cultivar was bred by crossing classic landraces from Nepal, Switzerland, and Thailand. It smells of a fresh pine forest dotted with hints of cherry. Harlequin helps mute pain and stress without fogging the mind. This cultivar typically sports a 1: This Sativa-dominant Hybrid smells of musky diesel but refreshes the soul like a warm cup of tea.
This cultivar is named after the cannabidiol pioneer, Lawrence Ringo. Shortly thereafter, other scientists began testing isolated cannabinoids on lab animals; notably, Walter S. Cannabis made another leap forward in when Israeli scientist Dr.
Raphael Mechoulam identified the structure of deltatetrahydrocannabinol, or THC. This discovery earned him godfather status of modern cannabis. In February of , Dr. Mechoulam teamed up with South American researchers to publish a study regarding cannabis and epilepsy.
This study is seen as one of the earliest double-blind studies of CBD on clinical subjects. Mechoulam and his team conducted included 16 people, many of whom were children, who all suffered from severe epilepsy. The results were startling: Every subject who received CBD experienced improvement in their condition with little to no side effects. This anticonvulsant study has since proven to be an integral milestone in the world of clinical marijuana research, but largely went unnoticed at the time.
In , a group of scientists researched and studied the effects of CBD on anxiety and found that it has potent anxiolytic, or anti-anxiety, properties as well. This groundbreaking moment paved the way for public support and lucrative research opportunities. Geoffrey Guy and Dr. Brian Whittle to found GW Pharmaceuticals, a company that would utilize clinical trials to unpack various cannabinoid formulations as potential therapies with the overriding focus of developing what would later be known as Sativex Nabiximols.
These mounting developments in the elicited a problem amongst cannabis cultivators across the US: Essentially, CBD had been selectively bred out of existence across the country. Years passed, and more studies rolled out with medically beneficial findings regarding cannabis until when Steep Hill Laboratory in Oakland, California, tested cannabis samples provided by Harborside Health Center to discover that a handful of cultivars contained more CBD than THC.
This discovery kicked other labs into gear. They wanted to study medical cannabis to understand and potentially calibrate their cannabinoid ratios. Soon thereafter, laboratories uncovered CBD-dominant strains boasting Cannabidiol is as versatile as THC — perhaps even more so. Through science and determination, CBD has worked its way into an entire host of products. Some of the most common methods include applying it sublingually, topically, or taking it in capsules.
Vaping cbd is regarded by many to be the most bio-available way to administer, and as such, this has led to an increase in the demand for CBD isolate. This form of CBD is different from full-spectrum CBD extract in that it only contains CBD and none of the other cannabinoids, terpenes, or healthy fatty acids that commonly result from the whole-plant extraction process.
Cannabis, with its complex chemical structure, contains over active cannabinoids aside from CBD. It also contains terpenes, which have anti-inflammatory properties, and are regarded as increasing the efficacy of cannabinoids. Although they are not rated as important as CBD when it comes medical benefits, some of these other cannabinoids have been found to have symptom alleviating qualities as well.
The cannabinoids CBN and CBG for example, are found in most full-spectrum extracts and studies have shown that both contain anti-inflammatory, anti-bacterial, and pain relieving properties. Whole-plant extracts typically contain a carefully measured amount of the cannabis plant's most prominent cannabinoid, THC, although usually not in a large enough amount to have any psychological effects. In many countries, a certain percentage of THC is illegal, so it is vital to know the amount of this cannabinoid when manufacturing products that contain full-spectrum CBD.
When present together, CBD and its cannabinoid colleagues, as well as terpenes, produce what is known as an entourage effect. The synergistic relationship between cannabinoids and terpenes has been shown to increase the healing properties of each. A study published by the Lautenberg Center for Immunology and Cancer Research, which aimed its focus on the effectiveness of CBD isolate compared to full-plant extract, supported this concept, stating in its summary that "in all of the tests, the isolated CBD was ineffective both before and after a certain dosage, while the effectiveness of the full-spectrum solution continued to increase as higher doses were administered.
The results all indicate that CBD is only effective against swelling and pain at a certain dose, and that cannabis solutions containing a full range of cannabinoids will continue to provide corresponding effects as the dosage is increased. Given the results of this study, it would seem to confirm that full-spectrum extract is preferable over CBD isolate for most CBD users, but CBD isolate is still frequently used and believed by some to be more effective than full-plant extract.
This belief is led by the idea that CBD is the only medically sought after cannabinoid in the cannabis plant, aside from THC. Many CBD isolate users are under the impression that by consuming only the CBD cannabinoid and no terpenes or any other "unnecessary" components of the plant, they are getting a more powerful or effective dose of CBD.
When vaping a CBD extract, which as stated previously, is considered to be the most efficient and quick-acting method of administering CBD, isolate users may feel that they are taking the most efficient route to CBD consumption. While this method might be efficient, the lack of entourage effect means the benefits are reduced when compared to full-spectrum CBD consumption. The fact that full-spectrum extracts invariably contain low levels of THC means that some users prefer to play it safe and stick to pure CBD by itself, out of fear of failing a drug test or experiencing a form of "high", although both of these occurrences have been found to be fairly unlikely.
THC is one of the cannabinoids involved in the "entourage effect" stated earlier so it is ideal for inclusion in CBD supplementation. THC mimics the action of anandamide, a neurotransmitter naturally produced in the human body, and binds to CB1 receptors in the endocannabinoid system found mostly in the brain.
The extremely low levels of THC in hemp make hemp oil non-psychoactive and safe for all ages to use. The wide range of benefits contained in full-spectrum CBD extracts means some CBD merchants have either ceased to sell, or scale down the promotion of CBD isolate, in comparison to the whole-plant extract variety.
Are CBD Isolates Safe to Use?
CBD isolate is what it sounds like: the extraction of CBD from the cannabis plant so that the subsequent product is “pure” CBD. Given how new CBD isolate is relative to other CBD products, we vital that you understand the potential power of CBD isolate products. This article breaks down two common terms used to describe CBD products -- full spectrum CBD and CBD isolate -- helps you decide which is.